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KMID : 0365220170540010001
Korean Journal of Public Health
2017 Volume.54 No. 1 p.1 ~ p.13
A study of disinfection through UV irradiation and silver nanoparticles combinations
Jung Hae-Yong

Ko Gwang-Pyo
Abstract
Objectives: The purpose of this study is to evaluate the antiviral capacity of the combinations Ultraviolet ?A (320 ?400 nm) or ?B (280 ?320 nm) (UV ?A or ?B) and silver nanoparticles (AgNPs).

Methods: Combined antiviral effects of ultraviolet-A or ?B and AgNPs were tested by plaque assay. Various combinations of UV-A or -B and AgNPs were exposed to tested viruses. Murine norovirus (MNV) and mouse hepatitis virus (MHV) were used as surrogates of human norovirus, known as a causing of viral gastroenteritis in humans and coronavirus, known as a cause of respiratory diseases in humans, respectively.

Results: AgNPs size, concentration and UV kind influenced antiviral capacity. MNV were more susceptive to AgNPs than MHV (p¡´0.05) while MHV were more susceptive to UV-B (p¡´0.05). Specially, the combinations of UV-B and 10 nm size (1 ppm or 10 ppm) AgNPs were more effective than UV-B treatment only (p¡´0.05).

Conclusion: These results suggest that combined antiviral effects of UV-B and AgNPs could be applied in disinfection processes for pathogenic viruses under various environmental conditions.
KEYWORD
Silver nanoparticle, ultraviolet, antiviral, murine norovirus, mouse hepatitis virus
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